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Portrai announces new spatial biology patent covering TME-PK™ framework

USPTO publication of a foundational patent covering Portrai's TME-PK framework — the spatial-pharmacokinetics workflow that turns tissue-level distribution into a quantified design input for ADCs and RPTs.

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Portrai Jan 10, 2026 - 3 min read
COMPANY NEWS

Portrai today announced the publication of a new spatial biology patent covering the TME-PK™ framework, a core component of the Prediction Engine that converts tissue-level distribution data into design-time pharmacokinetic inputs.

Why it matters

The patent claims cover the workflow by which spatial transcriptomics data is converted into per-cell-type drug exposure estimates — the quantitative bridge that lets in-silico predictions be tied to wet-lab and in-vivo validation across multiple modalities.

What’s next

The framework is already in production use across the Celltrion partnership and the POR001 / POR003 ADC programs. The published claims allow Portrai to extend the framework to additional partner programs without exposing core IP.

#TME-PK #IP #Patent #ADC #RPT

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